Recombinant Mouse Repressor of RNA polymerase III transcription MAF1 homolog (Maf1) from MyBioSource.com

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Recombinant Mouse Repressor of RNA polymerase III transcription MAF1 homolog (Maf1)

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Description

This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III). It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression